Neuro-ERG-V Veterinary Electroretinography System

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  • Highlights
  • Features
  • Specifications
  • Standard Set
  • Warranty
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Objective assessment of retinal function


Pet owners often come to veterinary clinics complaining weak or absent vision in their pets.  Yet, if the clinic is not equipped with objective-measure instruments, the veterinary doctor may very approximately assess vision using hurdle-tests and cotton-ball-test.  For objective vision assessment, the only method is Electroretinography.


Electroretinography (ERG) is a well-established technique for studying the retina function by means of recording its light-evoked electrical activity.  ERG is minimally invasive but provides accurate information about the retinal function.


Neuro-ERG-V Electroretinography System is a portable instrument ideal for the veterinary clinic, clinical networks, and experimental research in animals.


Indications for ERG include:


· Early detection of progressive retinal atrophy. In some dog breeds (Dachshund, English Cocker Spaniel, Labrador) ERG abnormalities may appear long before clinical signs become obvious (particularly, changes in the fundus of the eye).


· Sudden visual loss, blindness with the fundus appearing normal.  In such a case, ERG allows differentiating retinal pathology.


· Mature cataract when the fundus examination is impossible.  In this case, ERG helps assessing the retinal status and decide whether a surgery is indicated.


NEURO-ERG/V key features:


· Objective assessment of retinal function.


· Special ERG electrodes.


· Mini-ganzfeld stimulator.


· Suitable for a wide range of clinical purposes and research.

Variety of stimuli


Neuro-ERG-V can record retinal responses to a wide variety of visual stimuli – white, red, blue, green.  Visual stimulation can be left, right, and bilateral with the use of LED-goggles.


The recorded ERG data are displayed on the screen, stored in the computer database, shared, and printed out on any printer.


Eye-safe electrodes


Specially designed eye electrodes are safe, thereby preventing animal eye injury and the risk of infecting the eye.  At the same time, the electrodes enable better eye contact, lower impedance, and high-quality ERG recording.


Intelligent software with Veterinary-specific algorithm


The supplied software features a veterinary-specific algorithm.  It ensures automatic high-quality ERG recording, calculation of all temporal parameters, and report generation.


Exceptionally high-quality low-noise physiological preamplifiers, combined with high-efficiency digital filters and signal-processing algorithms, were specifically designed for NEURO-ERG/V based on extensive research and development.  They ensure excellent noise suppression, clear ERG recording, and reliable, reproducible calculation of ERG parameters.


This allows not only better diagnostics, but also reliable monitoring for any changes in follow-up retina assessments over prolonged periods of time.


Intra-operative ERG-monitoring


Designed to work in the electro-magnetically harsh OR environment, NEURO-ERG/V can be used as a reliable ERG monitor during surgery and post-operative outcome assessment.


Database and data export


ECG measurement data and interpretation, as well as exam reports, are saved in a well-organized software database.  The data and reports can be printed out either at the time of the assessment, or at a later time, and shared with a referring doctor or researcher.


ECG parameters can be exported to Excel spreadsheets and other statistical software for further data analysis making it an ideal tool for research projects.




The device is pocket-sized, and can be placed in a Carrying Case – along with a notebook computer – and can be powered from the computer.  Hence, it can be used both in the clinic and on an outpatient visit.


This means that long-term ERG monitoring system is always at hand, no matter where you perform surgery:  at your clinic or at a patient’s location.


Software compatibility


Neurosoft Software enables highly efficient, cost-effective operation through a number

of compatibility features:


Multiple Neurosoft Software:  Neurosoft Software for various Neurosoft instruments can be installed on the same computer – with no conflict between them.  Moreover, all software can share a single database – for greater convenience and work-flow efficiency.


Software compatibility


Neurosoft Software enables highly efficient operation – saving both capital and operating costs – through a number of compatibility features:


Multiple Neurosoft Software:  Neurosoft Software for various Neurosoft instruments can be installed on the same computer – with no conflict between them.  Moreover, all software can share a single database – for greater convenience and work-flow efficiency.


Multiple computers:  Although only one computer can be used for diagnostic test data recording, each Neurosoft Software License allows using software on an unlimited number of computers.  Thus, the data can be recorded on one computer, and then, the data can be shared, analyzed, reviewed on other computers – with no additional Software Licenses.


Other applications:  Neurosoft Software can operate on a computer with Microsoft Office applications – Word, Excel, Outlook, PowerPoint, Access, Project, as well as Adobe and accounting software.  This is particularly efficient in smaller clinics.


Internet:  Computers with Neurosoft Software installed can be connected to the Internet.  In an unlikely and rare event that a Microsoft Operating System update affects a Neurosoft software component, it can be restored by Neurosoft software re-installation, with no loss of data. 


Information system integration


Most clinics, networks and research institutions are equipped with information systems to store and process their data.  HL7 (Health Level 7) is the most commonly used interface engine for exchange, integration, sharing and retrieval of electronic data.


HL7-compatibility allows integrating Neuro-IOM-16-V into the information system of a veterinary clinic, clinical network, or research institution.




Electronic Unit – soft cloth gently wrung in phenols (Bacillotex® etc.), or 70% alcohol, or 0.5% chlorohexidine.


If dangerous virus contamination is suspected – aldehydes (Cidex® etc.), or chlorinates (Diversol BX® etc.).


Interface cables and power cords – soft cloth moistened with disinfectant, for example, 1% chloramine solution or 3% hydrogen peroxide solution.

Amplifier Channels

Number of channels


Sampling rate

200 Hz – 40 (160) kHz

Input Voltage range

20 µV – 50 mV

Ratio error of voltage measurement in the amplitude range:

· from 20 µV to 100 µV

· from 100 µV to 50 mV




within ± 15 %

within ± 5 %

Averaged EP voltage range

0.1 – 400 µV

Ratio error of averaged EP voltage measurement

± 10 %

Common-mode rejection ratio

≥ 100000 ( 100 dB)

Input equivalent noise level, RMS

0.5 µV

Input impedance

≥ 200 / 1000 MΩ

Input capacitance of amplifiers

25 / 22 pF

Patient leakage current

0.1 μA

Bandpass frequency response flatness:

· from 0.02 to 0.05 Hz and from 5 kHz to 10 kHz

· from 0.05 Hz to 5 kHz



from −30% to +5 %

from −10% to +5 %

Relative error of interval measurement

within ± 7 %

Relative error of calibration pulses recording

within ± 5 %

High-pass filter

0.02, 0.05, 0.1, 0.2, 0.3, 0.5, 1, 2, 3, 5, 10, 20, 30, 50, 100, 200, 300, 500, 1000, 2000, 3000 Hz

Low-pass filter

10, 20, 35, 50, 75, 100, 150, 200, 300, 500 Hz;

1, 2, 3, 5, 10 kHz


0.05, 0.075, 0.1, 0.15, 0.2, 0.25, 0.4, 0.5, 0.75,

1, 1.5, 2, 2.5, 4, 5, 7.5, 10, 15, 20, 25, 40, 50,

75, 100, 150, 200, 250, 400, 500, 750 μV/div.;

1, 1.5, 2, 2.5, 4, 5, 7.5, 10, 15, 20, 25, 40, 50 mV/div.

Relative error of sweep speed

± 1 %

Suppression ratio of power frequency by notch


40 dB

Visual stimulator

Maximum brightness of:

· LED goggles

· Mini-ganzfeld stimulator


1100 ± 110 cd/m2

1500 ± 150 cd/m2

Maximum brightness power of penlights:

· White

· Red

· Blue

· Green


0.20 ± 0.05 cd

0.30 ± 0.075 cd

0.15 ± 0.0375 cd

0.20 ± 0.05 cd

Brightness control range

-3…0 log units

Stimulus duration

0.05 – 1500 ms

Relative deviation of stimulus duration

within ± 10%

Stimulus frequency

0.01 – 100 Hz

Relative deviation of stimulus frequency

± 1 %

Left / right / bilateral stimulation using LED-goggles




General Parameters and Characteristics

Electronic Unit Interface with computer


Supply voltage:

· Electronic Unit

· Desktop PC-based system

· Notebook PC-based system


5 V DC (from USB)

 220 V AC (50 Hz)

 110 V AC (60 Hz) / internal battery


· Amplifier Unit

· Audio-Visual Stimulator Unit


190 × 140 × 50 mm

155 × 105 × 40 mm


· Amplifier unit

· Auditory-visual stimulator unit


≤ 1 kg

≤ 0.5 kg

Applied parts

CF type with protection against defibrillator discharge

Transportation Conditions


from -25 to +60°C


20 – 95% (non-condensing)

Atmospheric pressure

from 70 kPa

Storage Conditions


from +5 to +40°C


30-85% (non-condensing)

Atmospheric pressure

70-106 kPa

Operation Conditions


from +10 to +35°C


30-85% (non-condensing)

Atmospheric pressure

70-106 kPa



Electrical Safety and Electromagnetic Compatibility


Electromagnetic compatibility (EMC) is provided by conformance to IEC 60601-1-2-2014 (EN 60601-1-2:2015) requirements.


The system is intended for operation in electromagnetic environment, which special features are specified in Annex 2.


Portable and mobile RF communication equipment can affect the system operation.

The use of equipment not listed in Table 5 of this technical manual may result in increased emission and system decreased immunity.


As for safety, the system satisfies IEC 60601-1:2012 (AAMI/ANSI ES 60601-1:2005/(R2012) and A1:2012 and A2:2010/(R)2012, EN 60601-1:2006/A1:2013) and IEC 60601-2-40:2016 (EN 60601-2-40:2017). The electronic unit is supplied by regulated power supply through USB interface, it has double isolation and BF type applied parts according to IEC 60601-1:2012 (AAMI/ANSI ES 60601-1:2005/(R2012) and A1:2012 and A2:2010/(R)2012, EN 60601-1:2006/A1:2013).

Neuro-MVP Electronic Unit

1 pc.

Neuro-MVP Audio-Visual Stimulator Unit

1 pc.

SH-4H Holder

1 pc.

ERG Ring Electrode

2 pcs.

Disposable Subdermal Single Needle Electrode with Cable

3 pcs.

Mini-Ganzfeld Stimulator

1 pc.

Holder for Penlights and Mini-Ganzfeld Stimulator

1 pc.

USB Cable, A-B Type, 1.8 m

1 pc.

User Manual for Poly-Spectrum.NET Software

1 pc.

Carrying Case

1 pc.

License for the use of Neuro-MEP.NET Software with additional Neuro-MEP.NET/ERG Software Module

1 pc.


NOTE:  Computer (PC) is not included in Standard Set, but can be supplied as per Customer requirements.


Minimum requirements to PC:


· For the software based on Microsoft .NET platform dual core processor with ≥ 2.6 GHz clock rate and random-access memory (RAM) of ≥ 2 GB is required (4 GB is recommended).  For other software, the clock rate is desired to be ≥ 1200 MHz and RAM ≥ 512 MB.


· Either Windows 8 or Windows 10 operating system is required.  Both 32-bit and 64-bit editions are supported.


· A ground wire must be available as the third wire of the power outlet.  It is not allowed to connect the computers using adaptors that insulate the third wire.


Customized accessory sets


Accessory set, such as electrodes types and quantities, can be customized to specific needs of a clinic or research lab.


Contact us to discuss your accessory needs.

Electronic Unit limited warranty term – 2 years.


During the warranty term, repair is free, and if repair is impossible, Electronic Unit is replaced.  Warranty does not cover mechanical damage and unauthorized opening of Electronic Unit, and defects caused by misuse, and any product that has been altered or modified in any way.


Warranty repair is professionally performed at the Neurosoft Service Center in Ivanovo, RF.  Transportation costs to the Service Center are covered by the Customer, return transportation is covered by Neurosoft.


Customer pays return shipping charges.  We are responsible for the return shipping charges of replaced / repaired products.  Products found to be non-defective will be returned at customer's expense.


Extended warranty is available. Contact us for details.


Accessories (cables, bands, etc.) – 30 days.


Single-use items (electrodes, gels, pastes, etc.) are not covered.


Software updates are free of charge.  Please fill out the online Form to receive a download link to the version you are requesting.

1. The Electroretinogram


2. Electroretinography in Veterinary Ophthalmology (1973)


3. Guidelines for clinical electroretinography in the dog (2002)


4. Standardized Full-Field and Multifocal Electroretinography in Rabbits (2003)


5. Electroretinography (2007)


6. The normal electroretinogram in adult healthy Shih Tzu dogs using the HMsERG (2009)


7. Guidelines for clinical electroretinography in the dog: 2012 update (2012)


8. Electroretinography in dogs: a review (2014)


9. The electroretinogram and electro-oculogram: Clinical applications by Donnell J. Creel (2015)


10. Electroretinography: A biopotential to assess the function/dysfunction of the retina (2016)


11. Electroretinography in small animal practice (2017)


12. Electroretinogram of Human, Monkey and Mouse (2019)

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Neuro-ERG-V Veterinary Electroretinography System

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